Definition of COPD:
Chronic
obstructive pulmonary disease (COPD) is a preventable and treatable disease
characterized by persistent airflow limitation that is usually progressive and
associated with an enhanced chronic inflammatory response in the airways and
the lung to noxious particles or gases.
Disease under COPD:
1. Chronic bronchitis.
2.
Emphysema.
What are the Obstructive
pulmonary diseases:
Risk Factors for COPD:
1. Cigarette
smoking ( Most important risk factor; 95% in UK)
2. Indoor
air pollution ( Cooking with biomass fuels)
3. Occupational
exposure ( Coal dust, Silica & cadmium)
4. Recurrent
infection.
5. Low
socioeconomic status.
6. Cannabis
smoking.
7. Childhood
infection.
8. Maternal
smoking.
9. Low
birth weight.
10. Alfa 1-antiproteinase deficiency.
11. Airway hyper-reactivity.
Clinical Feature of COPD:
History:
·
Age (COPD is a disease of old age).
·
Duration of cough, sputum and
breathlessness.
·
Smoking.
·
Family history (positive).
·
Exacerbating factors such as cold
weather, smoking, exercise.
Symptoms:
·
Cough.
·
Sputum production.
·
Breathlessness.
·
Haemoptysis.
·
Morning headache (indicative of
hypercapnia)
·
Features of complications- e.g. features
of heart failure, pneumothorax etc.
Differential
diagnosis of COPD:
1. Chronic
bronchial asthma.
2. Bronchiectasis.
3. Congestive
cardiac failure.
4. Pulmonary
tuberculosis.
Complication
of COPD:
1. Pneumothorax-
due to rupture of emphysematous bulla into pleural space.
2. Recurrent
pulmonary infections.
3. Pulmonary
hypersensitivity.
4. Cor-pulmonale.
5. Congestive
cardiac failure.
6. Type-2
respiratory failure.
7. Secondary
polycythaemia- due to chronic hypoxia.